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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
17.58
Human Site:
Y294
Identified Species:
29.74
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y294
G
K
Y
S
T
S
L
Y
A
S
P
S
M
V
H
Chimpanzee
Pan troglodytes
XP_511585
968
108684
P298
D
Q
T
S
E
N
A
P
T
T
V
S
R
D
V
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y387
G
K
Y
S
T
S
L
Y
A
S
P
S
M
V
H
Dog
Lupus familis
XP_853409
975
109686
Y294
G
K
Y
S
T
S
L
Y
A
S
P
S
M
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y296
G
K
Y
S
T
S
L
Y
A
S
P
S
M
V
H
Rat
Rattus norvegicus
XP_573211
965
109012
H291
Y
A
S
P
S
M
V
H
E
G
V
A
V
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
T289
P
L
L
E
G
P
Q
T
D
G
V
T
I
K
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
Y299
G
K
H
V
T
G
F
Y
A
T
S
S
M
I
H
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
E288
T
L
Y
V
G
K
T
E
S
H
L
Y
A
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
L290
D
E
A
Y
Q
A
I
L
E
E
S
K
T
G
N
Honey Bee
Apis mellifera
XP_392044
968
110555
K289
I
L
K
R
F
A
N
K
P
S
D
I
Q
L
F
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
G302
F
F
P
A
L
F
V
G
E
S
S
F
G
L
Y
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
A314
D
Y
P
S
G
L
L
A
L
P
A
L
V
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
G294
L
G
I
H
S
Y
D
G
A
S
Y
N
V
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
0
N.A.
53.3
6.6
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
40
N.A.
13.3
N.A.
73.3
13.3
N.A.
26.6
20
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
15
8
8
43
0
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
0
0
0
0
8
0
8
0
8
0
0
8
8
% D
% Glu:
0
8
0
8
8
0
0
8
22
8
0
0
0
8
8
% E
% Phe:
8
8
0
0
8
8
8
0
0
0
0
8
0
0
8
% F
% Gly:
36
8
0
0
22
8
0
15
0
15
0
0
8
8
0
% G
% His:
0
0
8
8
0
0
0
8
0
8
0
0
0
0
36
% H
% Ile:
8
0
8
0
0
0
8
0
0
0
0
8
8
8
0
% I
% Lys:
0
36
8
0
0
8
0
8
0
0
0
8
0
8
0
% K
% Leu:
8
22
8
0
8
8
36
8
8
0
8
8
0
15
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
36
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
8
% N
% Pro:
8
0
15
8
0
8
0
8
8
8
29
0
0
0
8
% P
% Gln:
0
8
0
0
8
0
8
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
43
15
29
0
0
8
50
22
43
0
8
0
% S
% Thr:
8
0
8
0
36
0
8
8
8
15
0
8
8
8
0
% T
% Val:
0
0
0
15
0
0
15
0
0
0
22
0
22
36
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
36
8
0
8
0
36
0
0
8
8
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _